Table 4.
Negative Element Annotation Enrichment
| Annotation | Coverage (%) | P |
| CDS | 72.9 | < 0.0001 |
| 5’-UTR | 75.8 | 0.003996 |
| 3’-UTR | 74.2 | < 0.0001 |
| Messenger RNA | 72.6 | < 0.0001 |
| Transcribed | 72.9 | 0.001998 |
| ORegAnno | 86.4 | < 0.0001 |
NOTE.—Shown are the percentages of basepairs covered by predicted negatively selected elements along with P values for coverage enrichment. P values are determined using a permutation procedure, whereby predicted elements are randomly assigned locations in the subset of the genome studied and coverage of a given annotation is recorded. A total of 104 permutations are performed to determine a null distribution of coverage. CDS, coding sequence.