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HAI and neutralizing activity in immune sera of vaccinated mice
| Vaccine | HAIa |
Neutralization postvaccinationb | |
|---|---|---|---|
| Postvaccination | Postchallenge | ||
| Gag only | 8 | 1:20 | |
| HK68 4G headless HA plus Gag | 1 | 8 | 1:20 |
| PR8 4G headless HA plus Gag | 1 | 8 | 1:40 |
| PR8 full-length HA plus Gag | ≥128 | ≥128 | 1:20,480 |
The fold increase in titer over Gag-only prechallenge serum is shown.
The highest dilution of serum which achieved at least 50% neutralization is shown.
