Table 1.
Patient Characteristics for Eligible Patients (n = 63)
| Characteristic | Patients |
|
|---|---|---|
| No. | % | |
| Age, years | ||
| Median | 11 | |
| Range | 2.6-22 | |
| Sex | ||
| Male | 40 | 63.5 |
| Female | 23 | 36.5 |
| Diagnosis part A | ||
| CNS tumors | ||
| Malignant glioma | 7 | 23.3 |
| Medulloblastoma | 3 | 10.0 |
| Astrocytoma, mixed glioma | 2 | 6.6 |
| Ependymoma, NOS | 2 | 6.7 |
| Atypical teratoid/rhabdoid tumor | 1 | 3.3 |
| Non-CNS tumors | ||
| Soft tissue sarcomas | 6 | 19.9 |
| Ewing's sarcoma | 2 | 6.7 |
| Neuroblastoma | 2 | 6.7 |
| Osteosarcoma | 2 | 6.7 |
| Rhabdomyosarcoma, | 3 | 9.9 |
| Diagnosis part B | ||
| Acute lymphoblastic leukemia | 4 | 66.6 |
| Acute promyelocytic leukemia | 1 | 16.7 |
| Acute lmyeloid leukemia FAB M1 | 1 | 16.7 |
| Diagnosis part C | ||
| CNS tumor | ||
| Medulloblastoma | 5 | 35.7 |
| Primitive neuroectodermal tumor | 4 | 28.5 |
| Pineoblastoma | 2 | 14.3 |
| Atypical teratoid rhabdoid tumor | 1 | 7.1 |
| Non-CNS tumor | ||
| Neuroblastoma | 2 | 14.29 |
| Diagnotic part D | ||
| CNS tumor | ||
| Malignant glioma | 3 | 23.1 |
| Ependymoma | 2 | 15.4 |
| Medulloblastoma | 1 | 7.7 |
| Pineoblastoma | 1 | 7.7 |
| Non-CNS tumor | ||
| Rhabdomyosarcoma | 3 | 23.1 |
| Endodermal sinus tumor | 1 | 7.7 |
| Osteosarcoma | 2 | 15.4 |
| Prior therapy | ||
| Median No. prior regimens | 2 | |
| Range | 1-7 | |
| Prior radiation therapy | 45 | |
Abbreviations: NOS, not otherwise specified; FAB, French-American-British.