Table 1. TS activity of lung cancer cell lines classified according to histology.
| Cell line | Histology | TS activity (pmol per mg protein) |
|---|---|---|
| A549 | Adeno | 1.003±0.142 |
| H1975 | Adeno | 1.005±0.276 |
| H1650 | Adeno | 0.705±0.177 |
| PC9 | Adeno | 0.370±0.042 |
| PC9/ZD | Adeno | 0.635±0.148 |
| H358 | Adeno | 1.140±0.127 |
| PC3 | Adeno | 0.591±0.325 |
| SW1573 | Adeno | 1.695±0.544 |
| H460 | Large cell | 0.420±0.184 |
| H1299 | Large cell | 1.121±0.594 |
| H520 | Squamous | 1.755±0.813 |
| Calu-1 | Squamous | 4.805±3.061 |
| H226 | Squamous | 1.930±0.820 |
| LK2 | Squamous | 1.121±0.042 |
| PC1 | Squamous | 3.055±0.997 |
| EBC-1 | Squamous | 1.055±0.078 |
| PC10 | Squamous | 1.204±0.052 |
| QG56 | Squamous | 0.870±0.030 |
| HARA | Squamous | 2.590±0.340 |
| SBC-3 | SCLC | 5.795±0.247 |
| H82 | SCLC | 5.170±0.641 |
| H526 | SCLC | 1.125±0.092 |
| H69 | SCLC | 4.005±0.078 |
| MS-1 | SCLC | 2.555±0.474 |
| COR-L47 | SCLC | 3.760±0.560 |
| STC-1 | SCLC | 6.832±0.490 |
| SBC-1 | SCLC | 0.753±0.023 |
| Lu135 | SCLC | 3.698±0.190 |
| Lu134B | SCLC | 0.310±0.100 |
| RERF-LC-MA | SCLC | 1.413±0.183 |
Abbreviations: SCLC=small cell lung cancer; TS=thymidylate synthase.
Data are means±s.d. from three independent experiments.