Table 1.
Trends in expression levels and protein localization. Table of Z scores of subsets of gene classes characterized by protein and RNA mean, RNA lifetime, a, b, ratio of fluorescence detected on the edge compared to inside of the cell (E/I), and the degree of punctuate protein localization (DP). Leading strand corresponds to transcription in the same direction as the replication fork. PPI indicates protein-protein interactions. Z scores of more than 3 (indicated by red) represent a significantly larger value compared with the whole genome distribution with >99.9% confidence, while Z scores less than -3 (indicated by blue) represent a significantly smaller value.
Category | n | Protein | RNA | |||||
---|---|---|---|---|---|---|---|---|
Mean | a | b | E/I | DP | Mean | Lifetime | ||
All | 1018 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
Essential gene | 121 | 7.54 | 8.70 | 5.34 | -2.19 | -3.16 | 5.61 | 1.38 |
Nonessential gene | 894 | -2.74 | -3.16 | -2.02 | 0.74 | 1.30 | -1.99 | -0.32 |
Enzyme | 410 | 3.98 | 4.28 | 1.85 | -5.45 | -3.04 | 3.30 | 3.15 |
Translation | 17 | 4.04 | 3.36 | 3.30 | -0.86 | -3.52 | 3.30 | -2.44 |
Turnover, degradation | 13 | 3.05 | 3.60 | 2.08 | -0.99 | -1.76 | 2.37 | 2.14 |
Transcription factor | 98 | 0.61 | 1.27 | 0.71 | -2.95 | 4.29 | -0.53 | -2.53 |
Transporter | 88 | -0.84 | 0.45 | -1.44 | 7.78 | 0.96 | 2.28 | 3.29 |
Lagging strand | 425 | -1.42 | -1.95 | -0.82 | 0.74 | -0.07 | -4.42 | -3.63 |
Leading strand | 593 | 1.12 | 1.62 | 0.61 | -0.64 | 0.02 | 3.96 | 3.17 |
Gene length < 500 bp | 193 | 4.06 | 1.09 | 3.34 | -1.06 | -2.98 | 2.67 | -1.65 |
Gene length >= 500 bp | 825 | -1.92 | -0.55 | -1.72 | 0.57 | 1.45 | -1.26 | 0.73 |
Known PPI | 603 | 3.73 | 3.75 | 1.37 | -3.69 | -3.77 | 1.90 | 0.58 |
No known PPI | 415 | -4.68 | -4.65 | -1.73 | 4.28 | 4.43 | -2.25 | -0.61 |