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. Author manuscript; available in PMC: 2010 Aug 26.
Published in final edited form as: Hepatology. 2009 Mar;49(3):809–820. doi: 10.1002/hep.22724

Table 4. Baseline histologic characteristics by portal inflammation status, children only (N=205).

Portal Inflammation P-value*
None (N=20) Mild (N=156) More than mild (N=29) None vs. mild None vs. more than mild
Steatosis amount 0.20 1.0
 <5% 1 (5.0%) 1 (0.6%) 1 (3.5%)
 5-33% 8 (40.0%) 44 (28.2%) 11 (37.9%)
 34-66% 5 (25.0%) 51 (32.7%) 9 (31.0%)
 >66% 6 (30.0%) 60 (38.5%) 8 (27.6%)
Steatosis location <0.001 0.008
 Zone 3 (Central) 12 (60.0%) 34 (21.8%) 5 (17.2%)
 Zone 1 (Periportal) 1 (5.0%) 25 (16.0%) 7 (24.1%)
 Azonal 4 (20.0%) 12 (7.7%) 5 (17.2%)
 Panacinar 3 (15.0%) 85 (54.5%) 12 (41.4%)
Lobular inflammation score 0.37 0.55
 0 0 (0%) 0 (0%) 0 (0%)
 <2 under 20x mag 13 (65.0%) 75 (48.1%) 14 (48.3%)
 2-4 under 20x mag 6 (30.0%) 71 (45.5%) 12 (41.4%)
 >4 under 20x mag 1 (5.0%) 10 (6.4%) 3 (10.3%)
Ballooning 0.34 0.35
 None 11 (55.0%) 80 (51.3%) 14 (48.3%)
 Few 8 (40.0%) 49 (31.4%) 9 (31.0%)
 Many 1 (5.0%) 27 (17.3%) 6 (20.7%)
Fibrosis score 0.002 <0.0001
 None 13 (65.0%) 43 (27.9%) 2 (7.1%)
 Mild, zone 3 perisinusoidal 3 (15.0%) 7 (4.6%) 1 (3.6%)
 Moderate, zone 3, perisinusoidal 2 (10.0%) 7 (4.6%) 0 (0%)
 Portal/periportal only 0 (0%) 48 (31.2%) 13 (46.4%)
 Zone 3 and periportal, any combination 1 (5.0%) 30 (19.5%) 1 (3.6%)
 Bridging 1 (5.0%) 18 (11.7%) 10 (35.7%)
 Cirrhosis 0 (0%) 1 (0.7%) 1 (3.6%)
NASH diagnosis 0.008 <0.0001
 No NASH 10 (50.0%) 39 (25.2%) 2 (6.9%)
 Suspicious/borderline/indeterminate: Zone 3 pattern 3 (15.0%) 26 (16.8%) 7 (24.1%)
 Suspicious/borderline/indeterminate: Zone 1, periportal pattern 0 (0%) 43 (27.7%) 14 (48.3%)
 Yes, definite 7 (35.0%) 47 (30.3%) 6 (20.7%)

Note: Values are N=s (%)

*

P-values calculated using Fisher=s Exact Test