Table 3.
Proteins involved in oxidative stress identified in human subcutaneous abdominal adipocytes.
| Protein | Gene name | MW (kDa) |
Max. unique peptides |
Max. seq coverage (%) |
|---|---|---|---|---|
| Superoxide dismutase [Cu-Zn] | SOD1 | 16 | 4 | 31 |
| Superoxide dismutase [Mn], mitochondrial | SOD2 | 25 | 12 | 64 |
| Extracellular superoxide dismutase [Cu-Zn] | SOD3 | 26 | 2 | 10 |
| Catalase | CAT | 60 | 28 | 57 |
| Glutathione peroxidase 1 isoform 1 | GPX1 | 22 | 9 | 44 |
| Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | GPX4 | 27 | 9 | 45 |
| Probable glutathione peroxidase 8 | GPX8 | 24 | 2 | 10 |
| Peroxiredoxin-1 | PRDX1 | 22 | 15 | 52 |
| Peroxiredoxin-2 | PRDX2 | 22 | 13 | 37 |
| Thioredoxin-dependent peroxide reductase, mitochondrial | PRDX3 | 28 | 11 | 34 |
| Peroxiredoxin-4 | PRDX4 | 31 | 6 | 29 |
| Peroxiredoxin-5, mitochondrial | PRDX5 | 22 | 8 | 50 |
| Peroxiredoxin-6 | PRDX6 | 25 | 16 | 63 |
| Microsomal glutathione S-transferase 1 | MGST1 | 18 | 5 | 54 |
| Microsomal glutathione S-transferase 3 | MGST3 | 17 | 5 | 40 |
| Glutathione S-transferase kappa 1 | GSTK1 | 25 | 11 | 60 |
| Glutathione S-transferase Mu 1 | GSTM1 | 26 | 8 | 28 |
| Glutathione S-transferase Mu 2 | GSTM2 | 26 | 9 | 41 |
| Glutathione S-transferase Mu 3 | GSTM3 | 27 | 7 | 35 |
| Glutathione S-transferase omega-1 | GSTO1 | 28 | 3 | 14 |
| Glutathione S-transferase P | GSTP1 | 23 | 12 | 65 |
| Glutathione S-transferase theta-1 | GSTT1 | 27 | 7 | 29 |
| Glutathione S-transferase zeta 1 | GSTZ1 | 24 | 4 | 32 |
| Heme oxygenase 1 | HMOX1 | 33 | 5 | 25 |
| NAD(P)H dehydrogenase, quinone 1 | NQO1 | 31 | 8 | 44 |
| NAD(P)H dehydrogenase, quinone 2 | NQO2 | 26 | 9 | 54 |
| Amine oxidase [flavin-containing] A | MAOA | 60 | 23 | 53 |
| Amine oxidase [flavin-containing] B | MAOB | 59 | 20 | 49 |
| Glutamate--cysteine ligase catalytic subunit | GCLC | 73 | 2 | 4 |