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. Author manuscript; available in PMC: 2011 Sep 3.
Published in final edited form as: Cell Stem Cell. 2010 Sep 3;7(3):279–282. doi: 10.1016/j.stem.2010.08.009

Table 2.

Tumor-initiating capacity of sorted pancreatic cancer cells in NOD/SCID and NSG mice. The TIC frequency was calculated using a limiting dilution analysis (with 95% confidence intervals) and significance determined by chi-squared analysis.(Hu and Smyth, 2009). See Figure S1 for gating strategy of sorted cells and histology of tumors.

Tumor formation
Cell Phenotype Mouse Xenograft 5,000 1,000 500 100 TIC frequency−1 (95% CI) P- value
ALDH+ NSG Panc253 4/4 3/4 1/4 300 (190–500) 0.471
Panc219 4/4 3/4 2/4
Panc140 4/4 2/4 2/4
NOD/SCID Panc253 4/4 4/4 2/4 330 (200–530)
Panc219 4/4 3/4 2/4
Panc140 3/4 1/4 0/4
CD44+CD24+ NSG Panc253 4/4 3/4 240 (130–450) 0.435
Panc219 2/2 3/4 1/4
Panc140 1/2 1/3
NOD/SCID Panc253 4/4 3/4 180 (100–330)
Panc219 2/2 3/4 4/4
Panc140 1/2 1/3