Skip to main content
. Author manuscript; available in PMC: 2011 Mar 16.
Published in final edited form as: Nature. 2010 Aug 15;467(7313):338–342. doi: 10.1038/nature09367

Table 1.

Numbers of differentially methylated regions (DMRs) identified in myeloid versus lymphoid commitment

Comparisons (Group 1 vs. Group 2) Numbers of DMRsa
DMRs within 2 kb of a transcriptional start site Locations of DMRs relative to CpG islands (%)
Group 1>Group 2 Group 1<Group 2 Islands Shoresc >2 kbc

MPPFL− vs. MPPFL+ 18 112 69 56.1 35.4 8.5

MPPFL+ vs. CLP 302 46 182 52.4 39.0 8.6
CLP vs. DN1 203 3017 2433 17.8 80.7 1.5
DN1 vs. DN2 3923 174 3125 18.9 80.3 0.7
DN2 vs. DN3 47 12 13 5.0 78.3 16.7

MPPFL+ vs. CMP 149 1412 1129 17.3 81.2 1.5
CMP vs. GMP 768 11 554 16.8 81.1 2.1

DN1 vs. GMP 1011 122 773 16.8 78.2 5.0
a

Area cutoff of 2.0 was used to calculate the number of DMRs (see online Methods).

b

Shores were defined for this table as overlapping islands by <50% and/or extending up to 2 kb from an island.

c

Regions 2 kb from an island.