Table 4.
Association between MR-UC and known UC loci
| Chr* | SNP | Position* | Minor Allele | P-value | Odds Ratio | Loci of Interest | Reference(s) |
|---|---|---|---|---|---|---|---|
| 1 | rs3024505 | 205006527 | A | 2.21E-03 | 1.43 | IL-10 | 3, 44 |
| 2 | rs2288750 | 241371118 | A | 2.07E-03 | 1.51 | KIF1A | 44 |
| 5 | rs7709212 | 158696755 | G | 1.29E-03 | 1.36 | IL-12B | 1 |
| 6 | rs28772724 | 32617335 | A | 1.34E-08 | 0.48 | MHC | 2, 3, 4, 6 |
| 9 | rs11554257** | 116644891 | G | 1.39E-06 | 1.82 | TNFSF15 | 64 |
| 12 | rs1558744 | 66790859 | A | 9.03E-05 | 1.45 | IFNG | IL-26 | 4 |
| 16 | rs1182968** | 67131446 | G | 5.66E-04 | 0.66 | ZFP90 | 45 |
| 17 | rs2305480 | 35315722 | A | 1.43E-03 | 1.35 | GSDML | ORMDL3 | 44 |
Association results observed in MR-UC vs. Non-IBD controls (analysis-III), with the exception of rs2288750, which was observed in MR-UC vs. Non-MR-UC analysis-I only (in bold).
**
SNP found to be associated in both analysis-I and –III.
*
Defined using dbSNP Build 129.