. Author manuscript; available in PMC: 2011 Dec 1.

Published in final edited form as: Curr Opin Immunol. 2010 Oct 20;22(6):698–705. doi: 10.1016/j.coi.2010.09.002

Table 3.

Susceptibility Genes for SSc

Chromosome	Gene	SNPs	Population	Reference
6p21.32	HLA-DPB1, DPB2 HLA-DQB1	rs3128930, rs7764491, rs7763822, rs3128965, rs3117230, rs7763822, rs7764491, rs3117230, rs3128965 rs6457617	Korean, European European	[33] [33]
2q32.3	STAT4	rs7574865, rs11889341, rs8179673, rs10181656, rs3821236	European, Japanese	[44]
7q32	TNPO3-IRF5	rs2004640, rs2280714, rs10954213, rs10488631, rs12537284, rs4728142	European, Japanese	[35,36]
4q24	BANK1	rs10516487, rs17266594	European	[41]
8p23.1	C8orf13-Blk	rs2736340, rs13277113	European	[42,43]
17q21.32	TBX21	rs11650354, rs17699436	European	[[44]
1q25.1	TNFSF4	rs1234314, rs2205960, rs844644, rs844648	European	[47]
10q24	FAS	rs1800682 (G-670A)	European	[45,46]
6q23.1	CTGF	rs6918698 (G-945C), rs9399005	European, Japanese	[37–40]
1q22-23	CD247	rs2056626	European	[34]