Table 2.
Genome-wide significant bipolar disorder loci tested in schizophrenia
| Original study results |
Schizophrenia |
|||||||
|---|---|---|---|---|---|---|---|---|
| Study | Locus | SNP | P-value | OR | (95% CI) | P-value | OR | (95% CI) |
| McMahon et al. (13) | PBRM1 | rs2251219 | 1.7 × 10−9 | 0.88 | (0.85–0.92) | 1.3 × 10−4a | 0.77 | (0.68–0.89) |
| Ferreira et al. (15)b | ANK3 | rs1938526 | 1.3 × 10−8 | 1.40 | – | 0.82 | 0.97 | (0.72–1.29) |
Study, source of genome-wide significant finding; P-value, Armitage trend test; OR, odds ratio; CI, confidence interval.
aOne-tailed P-value where OR is in the same direction as the original study.
bNo details of 95% CI given in the original manuscript.