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. 2010 Dec 21;11:605. doi: 10.1186/1471-2105-11-605

Table 1.

Estimated false negative rate of LowBP-LC restricted to interactions involving well-studied proteins.

Well-studied cutoff Uetz-Screen Ito-Core CCSB-YI1 Y2H-Union Tarassov HT-Union
100 0.64 0.66 0.66 0.68 0.63 0.67
105 0.63 0.65 0.65 0.67 0.61 0.66
110 0.64 0.66 0.65 0.67 0.61 0.66
115 0.65 0.66 0.64 0.67 0.61 0.66
120 0.66 0.65 0.63 0.66 0.62 0.65
125 0.66 0.66 0.65 0.67 0.61 0.66
130 0.63 0.49 0.63 0.63 0.62 0.63
135 0.60 0.49 0.62 0.61 0.62 0.62
140 0.60 0.47 0.62 0.61 0.64 0.62
145 0.62 0.45 0.61 0.60 0.64 0.61
150 0.63 0.45 0.61 0.61 0.64 0.62

The false negative rate is computed separately with each high-throughput dataset, using a cutoff to consider proteins well-studied ranging from 100 to 150 and a reference FDR for CCSB-YI1 set at 0.25.