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. Author manuscript; available in PMC: 2011 Mar 23.
Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2009 May;48(5):484–500. doi: 10.1097/CHI.0b013e31819c23d0

Table 3.

8-Year Outcomes (M, SD or %) for MTA and LNCG

Group Mixed Effects or Multinomial Model Results F or X2 (df), p-value
MTA LNCG Group (MTA vs LNCG) Time Group * Time Effect Size

ADHD Symptoms N=436 N=232
SNAP Inattention Parent 1.40 (0.76) 0.48 (0.48) 512.13 (1)
.0001
14.48 (2)
.0007
14.83 (2)
.0006
(1.36)
SNAP Inattention Teacher 1.30 (0.74) 0.73 (0.64)
SNAP Hyper/Impulsive Parent 0.77 (0.68) 0.15 (0.24) 384.46 (1)
.0001
189.92 (2)
.0001
39.06 (2)
.0001
(1.09)
SNAP Hyper/Impulsive Teacher 0.64 (0.67) 0.24 (0.40)
ODD Symptoms
SNAP ODD Parent 1.03 (0.79) 0.37 (0.46) 253.12(1)
.0001
26.64 (2)
.0001
12.17 (2)
.0023
(.95)
SNAP ODD Teacher 0.51 (0.65) 0.22 (0.42)
Antisocial Behavior
Aggression Conduct Parent 1.15 (0.22) 1.04 (0.07) 135.89 (1)
.0001
32.30 (2)
.0001
10.46 (2)
.0054
(.60)
Aggression Conduct Teacher 0.15 (0.21) 0.05 (0.11)
Delinquency Severity Rating 1.62 (1.57)
1.10 (1.50)
107.90 (1)
.0001
32.17(3)
.0001
7.66 (3)
.0536
(.34)
 % 3 or higher 36.4 21.8
Police Contacts, % once 39.0 14.0 58.75 (1)
.0001
(.47)
 % two or more times 10.9 3.2
Arrested, % once 19.8 11.6 18.82 (1)
.0001
(.38)
 % two or more times 7.0 2.6
Impairment: CIS 1.09 (0.70) 0.49 (0.46) 238.30 (1)
.0001
32.83 (2)
.0001
6.60 (2)
.0369
(.96)
Depression: CDI 7.31 (7.27) 5.77 (7.21) 17.37 (1)
.0001
39.95 (3)
.0001
3.79 (3)
.2846
(.21)
Anxiety: MASC 82.8 (17.7) 82.9 (15.7) 0.15 (1)
.6975
874.42 (3)
.0001
1.31 (3) .7257
Academic
WIAT Reading 95.7 (13.8) 102.0 (11.6) 21.30 (1)
.0001
83.15 (2)
.0001
3.19 (2)
.2025
(.48)
WIAT Math 94.6 (16.4) 105.4 (16.6) 44.27 (1)
.0001
142.01 (2)
.0001
12.68 (2)
.0018
(.66)
SSRS Academic Performance Teacher 3.08 (0.82) 3.54 (0.83) 53.49 (1)
.0001
0.12 (2)
.9436
10.82 (2)
.0045
(.56)
Grade Point Average 2.75 (0.57) 3.02 (0.61) 19.17 (1)
.0001
(.45)
Grade Retention % 37.3 17.9 31.38 (1)
.0001
(.43)
Social Functioning
SSRS Social Skills Parent 1.24 (0.28) 1.46 (0.22) 268.22 (1)
.0001
29.06 (2)
.0001
14.68 (2)
.0006
(.84)
SSRS Social Skills Teacher 1.19 (0.30) 1.37 (0.30)
Other
Psychiatric Hospitalizations, % 10.4 1.3 12.62 (1)
.0004
(.44)
Accident/citation/ticket, % 22.2 27.6 1.37(1)
.2417
Diagnosis
ADHD, % 30.2 2.2 223.36 (1)
.0001
6.74 (2)
.0343
3.47 (2)
.1768
(.88)
 ADHD Combined, % 8.8 0
 ADHD Hyperactive, % 2.5 0
 ADHD Inattentive, % 18.9 2.2
ODD/CD, % 25.1 4.7 144.72 (1) 11.87 (3) 2.38 (3) (.60)
 Conduct, % 8.1 2.2 .0001 .0079 .4973
 ODD, % 17.7 2.6
Anxiety/Depression, % 10.4 5.2 16.06 (1)
.0001
10.27 (3)
.0164
1.39(3)
.7088
(.19)

Note. Where applicable, means for parent and teacher reports are provided separately but regression analyses yielded one overall test of treatment, time, and treatment-by-time effects. For four variables (police contacts, arrested, diagnoses of ADHD and ODD/CD), additional descriptive statistics are provided for interpretation but analyses were based on the first variable listed. SNAP measures rated 0- not at all to 3- very much; Aggression Conduct Parent measure rated 1-never to 4- often; Aggression Conduct Teacher measure rated 0- not at all true to 3- very much true; CIS (Columbia Impairment Rating Scale) rated 0- no problem to 4- a very bad problem; CDI (Children's Depression Inventory) rated 0 – Best to 2 – Worst, 27 items summed; MASC (Multidimensional Anxiety Scale for Children) rated 1 – never true to 4 – often true, 45 items summed; SSRS (Social Skills Rating System) Academic Performance Teacher measure rated 1-lowest 10% of class to 5- highest 10% of class; SSRS Social Skills measures rated 0- never to 2-very often. School services data not available for LNCG. Results reported from analyses without age as covariate but with IQ controlled for outcomes in academic domain. Only effect sizes for contrasts significant at p<.05 are reported. Effect sizes were calculated on observed data using Cohen'd d for means (SD) and Cohen's h for proportions (0.2-small, 0.5-medium, 0.8-large) after confirming correspondence with least squares estimated mean differences (which are less clinically interpretable). N=31 LNCG cases with ADHD at recruitment removed from analyses; results were not appreciably different when they were included. MTA = Multimodal Treatment Study of Children with Attention-Deficit / Hyperactivity Disorder; LNCG = Local Normative Comparison Group; SNAP = Swanson, Nolan, Pelham Rating Scale; ODD/CD = Oppositional Defiant Disorder / Conduct Disorder. WIAT = Wechsler Individual Achievement Test; CIS = Columbia Impairment Rating Scale; CDI = Children's Depression Inventory