Table 2.
The Acylcarnitine Factor, a One-Factor Solution by Principal Components Analysis
| Metabolites | Description | Factor Loading |
| C10-OH/C8-DC, C12:1, C14:1-OH/C12:1-DC, C12-OH/C10-DC, C14:1, C12, C14, C14:2, C16:1, C16:2, C8:1-DC, C18:1, C10:1, C2, C18:1-OH/C16:1-DC, C14-OH/C12-DC, C16:1-OH/C14:1-DC, C16 | Mainly by-products of beta-oxidation (medium- and long-chain acylcarnitines, ranging from C10 to C18) and acetylcarnitine (C2) | ≥0.70 |
| C18:2, C6-DC, C6:1-DC/C8:1-OH, C8:1, C10:2, C4-OH, C10, C10:3, Ci4-DC/C4-DC, C20:1-OH/C18:1-DC, C6, C20, C18 | 0.51–0.69 | |
| C16-OH/C14-DC, C8, C5-OH/C3-DC, C5-DC, C20-OH/C18-DC, C18:2-OH, C18-OH/C16-DC, C3, C5’s, C4/Ci4, C7-DC, C22, C20:4, C5:1 | By-products of amino acid catabolism (odd-chain acylcarnitines) and long-chain fatty acid oxidation (C16 to C22) | ≤0.50 |
Note: Metabolites are listed in descending order according to their factor load. DC = dicarboxy; OH = hydroxy.