Table 10.
Nuclear import cargos of the Transportin-SRs and yeast Kap111p.
| Cargo | Location of NLS | Other Kapβs that also mediate import |
|---|---|---|
|
Trn-SR/SR2 | ||
| ASF/SF2 [131–134] | Residues 198-248 (RS domain) | |
| SC35 [131,132] | Residues 90-222 (RS domain) | |
| TRA2α [132,134] | RS domain | |
| TRA2β [132,134] | RS domain | |
| HPV E2 [143] | RS domain | |
| RBM4[143] | C-term ala-rich domain | |
| ALEX3 [143] | Not determined | |
| BAB71287 [143] | Not determined | |
| BAP1 [143] | Not determined | |
| MLF2 [143] | Not determined | |
| ODF2 [143] | Not determined | |
| dASF, dSC35, d9G8, Rbp1, B52, RSF1 [135] | RS domain | |
| HIV1 IN [83,84,88] | catalytic core | Importin-α/β, -β, -7, -β/-7 [81,82,85–87,89,90] |
|
Kap111p (Mtr10p) | ||
| Gbp2p [139] | N-terminus | |
| Hrb1p [140] | RS domain | |
| Npl3p [141,142] | Residues 283-414 | |
| tRNAs [144] | Not determined | |