Table 2.
PY-NLS containing Kapβ2 and Kap104p cargos.
| Cargo | Location of NLS | Other Kapβs that also mediate import |
|---|---|---|
|
Kapβ2 | ||
| PQBP-1 [18,174,175] | Residues 161-187 | |
| YBP1 [18,174,176] | Residues 176-196 | |
| PABP2 [177] | Residues 280-306 | |
| EWS [18,174,178] | Residues 630-656 | |
| FUS [18,174,178] | Residues 500-526 | |
| SAM68 [18,174,179] | Residues 414-440 | |
| hnRNP M [18,45,174] | Residues 38-64 | |
| hnRNP A1 [18,40] | Residues 263-289 | |
| hnRNP A0 [43] | Residues 264-290 | |
| hnRNP A2 [180] | Residues 293-319 | |
| hnRNP A3 [181] | Residues 334-360 | |
| hnRNP D [182,183] | Residues 329-355 | |
| hnRNP F [18,174,184] | Residues 184-210 | |
| hnRNP H1 [174] | Residues 184-210 | |
| JKTP-1 [185] | Residues 394-420 | |
| TAP (NXF1) [46,186–188] | Residues 49-75 | |
| HuR [174,189,190] | Residues 212-238 | |
| HEXIM1 [18,174,191] | Residues 141-167 | Importin-α binding [192] |
| RB15B [18] | Residues 258-284 | |
| Clk3 [18] | Residues 75-101 | |
| WBS16 [18] | Residues 75-101 | |
| Cyclin T1 [18,174] | Residues 661-687 | |
| TAFII68 [178] | Residues 566-592 | |
| CPSF6 [18,174] | Residues 364-390 | |
| HCC1 [18] | Residues 73-99 | |
| SOX14 [18] | Residues 72-98 | |
| ETLE [193] | Residues 317-343 | |
|
Kap104p | ||
| Nab2p [43,47,48] | Residues 201-251 | |
| Hrp1p [43,49] | Residues 494-534 | |
| Tfg2p [44] | Residues 172-206 | Potential secondary import by Kap120p, Kap108p |