TABLE 1.
COMPARISON OF DEMOGRAPHIC AND CLINICAL CHARACTERISTICS OF PATIENTS WITH AND WITHOUT ACUTE LUNG INJURY
| Characteristic | Patients without ALI (n = 82) | Patients with ALI (n = 62) | P Value |
|---|---|---|---|
| Age, yr: mean ± SD | 52 ± 21 | 44 ± 18 | 0.02 |
| Female sex, n (%) | 26 (32%) | 12 (19%) | 0.10 |
| Private insurance, n (%) | 32 (41%) | 21 (35%) | 0.22* |
| Race, n (%) | |||
| White | 44 (54%) | 41 (66%) | |
| African-American | 10 (13%) | 8 (13%) | 0.26 |
| Asian-American | 23 (28%) | 12 (19%) | |
| Latino ethnicity | 15 (19%) | 13 (21%) | 0.80 |
| Traumatic brain injury, n (%) | 54 (66%) | 45 (73%) | 0.39 |
| History of alcohol abuse, n (%) | 20 (24%) | 14 (23%) | 0.80 |
| History of alcohol abuse, alcohol withdrawal, alcoholic cirrhosis, high score on AUDIT, or high blood alcohol level, n (%) | 24 (29%)† | 19 (31%)‡ | 0.86 |
| History of active illicit drug use, n (%) | 11 (13%) | 8 (13%) | 0.93 |
| History of active smoking, n (%) | 21 (26%) | 22 (36%) | 0.20 |
| History of asthma, n (%) | 3 (4%) | 6 (10%) | 0.19 |
| History of COPD, n (%) | 0 (0%) | 2 (3%) | 0.20 |
| Injury Severity Score, mean ± SD | 24 ± 15 | 33 ± 15 | 0.0003 |
| Chest component of injury score, mean ± SD | 0.9 ± 1.6 | 1.9 ± 1.9 | 0.0009 |
| Units pRBCs transfused in first 24 h, median (IQR) | 0 (0, 2) | 3 (0, 9) | <0.0001 |
| Units FFP transfused in first 24 h, median (IQR) | 0 (0, 2) | 2 (0, 8) | 0.0001 |
| Units platelets transfused in first 24 h, median (IQR) | 0 (0, 0) | 0 (0, 1) | <0.0001 |
| Day of ALI, median (IQR) | — | 1 (0, 3) | — |
Definitions of abbreviations: ALI = acute lung injury; AUDIT = Alcohol Use Disorders Identification Test; COPD = chronic obstructive pulmonary disease; FFP = fresh frozen plasma; IQR = interquartile range; pRBCs = packed red blood cells.
*
P value for comparison overall of types of insurance.
†
Of the four subjects with no chart history of alcohol abuse, two were classified as alcohol abusers based on AUDIT score and two based on high blood alcohol level.
‡
Of the five subjects with no chart history of alcohol abuse, all five were classified as alcohol abusers based on high blood alcohol levels.