Table 1.
Tumor spectra
|
Brcaltr/tr
|
Brcaltr/tr/p53−/−
|
Brcaltr/tr/p53+/−
|
|---|---|---|
| 92 tumors (76 mice) | 9 tumors (8 mice) | 8 tumors (7 mice) |
| 32 lymphomas (35%) | 8 lymphomas (89%) | 3 lymphomas (37%) |
| 19 mediastinal | ||
| 12 nodal | ||
| 1 thymic | ||
| 10 Sarcomas (11%) | 1 sarcoma (11%) | 1 sarcoma (13%) |
| 2 angiosarcomas | Angiosarcoma | Osteosarcoma |
| 8 spindle cell sarcomas | ||
| 7 retroperitoneal | ||
| 1 dermal | ||
| 41 adenomas/carcinomas (44%) | 3 adenomas/carcinomas (37%) | |
| 12 breast | 2 breast | |
| 13 lung | 1 lung | |
| 13 liver | ||
| 2 uterus | ||
| 1 colon | ||
| 9 other tumor types (10%) | 1 other type (13%) | |
| 4 undifferentiated | Angiopericytoma | |
| 4 hemangiomas | ||
| 1 ovarian teratoma |