Fig. 1.
Expression of CXCR6 is upregulated on CD8 T cells in the lung after i.n. Ad85A immunization. BALB/c mice were immunized with Ad85A i.n. or i.d. Five weeks later, CD8+ T cells from several tissues were analyzed for expression of CXCR6. The results shown are the mean values for 3 mice per group for lung, spleen, and liver samples ± standard deviations (SD), while the facial lymph nodes and blood were pooled from the same mice for analysis, and their results are representative of results obtained in two independent experiments. *, P = 0.03 by Mann-Whitney testing of the data from two experiments. (B) The absolute numbers of CD8 CXCR6+ cells in the lungs and spleen were also determined. The results shown are representative of two independent experiments.