Figure 1.
miRNA array and real-time PCR detect that the miR-29 family is lost in the UUO kidney of Smad3 WT, but increases in Smad3 KO mice. (A) miRNA expression profile in the UUO kidney of Smad3 WT and KO mice. (B) List of fold changes of miRNAs in the UUO kidney in Smad3 WT and KO mice. The data are normalized to normal Smad3 WT or KO mice. (C) Real-time PCR results of miR-29 family members expression in Smad3 WT and KO mice. Each bar represents the mean ± SEM for at least five mice. *P < 0.05, **P < 0.01, ***P < 0.001 versus normal mice; #P < 0.05, ##P < 0.01, ###P < 0.001 versus Smad3 WT UUO.