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. 1966 Mar;91(3):997–1003. doi: 10.1128/jb.91.3.997-1003.1966

Induction of Penicillinase by Staphylococci In Vitro and In Vivo

Luc Eyckmans a,1, Edward W Hook a
PMCID: PMC315990  PMID: 5929771

Abstract

Eyckmans, Luc (Cornell University Medical College, New York, N.Y.), and Edward W. Hook. Induction of penicillinase by staphylococci in vitro and in vivo. J. Bacteriol. 91:997–1003. 1966.—Staphylococci in mice with peritoneal infection showed no significant increase in penicillinase activity 6 hr after administration of penicillin G. In contrast, induction of penicillinase was readily demonstrated in leukopenic animals under similar conditions. Induction of penicillinase by staphylococci in vitro was inhibited by including leukocytes and immune serum in the mixtures. The role of leukocytes in inhibiting induction of penicillinase by staphylococci in response to penicillin was investigated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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