Figure 5.
The ROC curves of flat NESsential and NetNES at the residue level. Because many residues are assigned a score of zero (see Supplementary Data), there is a big jump of measurable performance (dashed line) for both methods. Each dashed line connects two specific points in ROC space: one end represents the false positive rate (FP rate) and true positive rate (TP rate) obtained by using the smallest nonzero score as a threshold, while the other end (1, 1) represents the unconditional assignment of all residues as NES positions. The AUC was calculated for each curve including the dashed line.