Table 3.
Frequency of somatic cancer gene mutations identified through routine clinical genotyping across gastrointestinal malignancies.
More than one mutation was identified in some samples.
aSmall intestine cancers were included in the total cohort numbers but not listed as a subgroup because of the small number of samples.
Abbreviations: APC, adenomatous polyposis coli; CTNNB1, catenin β-1; EGFR, epidermal growth factor receptor; IDH1, isocitrate dehydrogenase 1; JAK2, Janus kinase 2; KRAS, Kirsten-ras; PIK3CA, phosphatidylinositol 3-kinase, catalytic, alpha; PTEN, phosphatase and tensin homologue deleted on chromosome ten; TP53, p53 tumor suppressor.