Fig. 3.
Inhibition of specific[3H]N-methylspiperone (150 pM) binding to intact cells transfected with the background construct, C118S, or with I184C, C182A/I184C, and C182A D2Rs resulting from 2-min applications of 2.5 mM MTSEA (A)or 10 mM MTSES (B). The mean and SEM are shown. The number of independent experiments for each mutant is shown next to the bars. Solid bars indicate mutants for which inhibition was significantly different (P < 0.05) from C118S by one-way ANOVA and Dunnett's post hoc test.