Table 3.
Comparison of Key Network Statistics for Core and Expanded Networks with Summary Statistics from a Random Sampling of 12 Other PPI Networks
| |
AD Networks |
Other Networks |
||||
|---|---|---|---|---|---|---|
| Parameter | Core | Expanded | Mean | Min | Max | SD |
| Number of nodes | 775 | 4945 | 3395.7 | 419 | 8674 | 2614.4 |
| Number of edges | 2204 | 26064 | 9579.8 | 1089 | 31656 | 10,600.3 |
| Average clustering coefficient | 0.225 | 0.154 | 0.086 | 0.006 | 0.195 | 0.063 |
| Diameter | 9 | 9 | 14.2 | 4 | 29 | 7.1 |
| Average closeness centrality | 0.313 | 0.048 | 0.076 | 0.025 | 0.182 | 0.053 |
| Average shortest path | 3.179 | 3.618 | 5.126 | 3.390 | 8.449 | 1.616 |
| Average degree | 5.623 | 10.542 | 4.419 | 2.229 | 6.815 | 1.548 |
| Power law coefficient | 1.302 | 1.700 | 1.679 | 1.135 | 1.987 | 0.243 |
| Density | 0.0070 | 0.0020 | 0.0023 | 0.0001 | 0.0110 | 0.0029 |
See Table 1 for a description of parameters. “Min” is the minimum value of the indicated parameter among all the other networks, while “Max” is the maximum value. “SD” is the standard deviation of the parameter.