Fig. 1.
Microarray analysis indicated that miR-132 expression was down-regulated in the PFC from schizophrenia subjects. (A) qPCR validation of miR-132 expression in the PFC from control (CON), schizophrenic (SCZ), and bipolar disorder (BPD) subjects from two separate populations (SMRI, HBB). Lines show mean + SEM, *P < 0.05, **P < 0.01. (B) Significant up-regulation of the expression of several putative miR-132 targets was validated by qPCR in the HBB samples. Group size for each sample set is presented in Tables S1 and S2; error bars = SEM.