Table 1.
Sample Demographics and Baseline Clinical Characteristics and Cognitive Measures
| Characteristics | N = 74 |
|---|---|
| Female, no. (%) | 38 (51.3) |
| Caucasian, no. (%) | 65 (87.8) |
| Age at initial test, mean ±SD | 73.8 ± 7.0 |
| Years of education, mean ±SD | 15.4 ± 3.0 |
| Span of years tested, mean ±SD | 6.9 ± 2.5 |
| Number of tests, median (range) | 5 (2, 10) |
| Average initial cognitive performance | |
| Global | 101.0 ± 14.7 |
| Verbal Memory | 106.3 ± 15.3 |
| Executive | 98.9 ± 13.3 |
| MMSE | 29.1 ± 1.3 |
| Presence of vascular factor, no. (%) | |
| Hypertension | 51 (68.9) |
| Hyperlipidemia | 28 (37.8) |
| Diabetes | 8 (10.8) |
| Obesity (N=67) | 19 (28) |
| Coronary artery disease | 8 (10.8) |
| Cerebrovascular disease | 3 (4.0) |
| Baseline key MRI measures | |
| Silent Brain Infarct, no. (%) | 20 (27.0) |
| White Matter Hyperintensities (% ICV) | 0.6 ± 0.7 |
| White Matter Hyperintensities (cc) | 7.6 ± 8.4 |
| Hippocampal Volume (% ICV) | 0.3 ± 0.04 |
| Cortical Gray Matter (% ICV) | 39.4 ± 2.2 |
ICV = intracranial volume.