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. Author manuscript; available in PMC: 2012 Apr 4.
Published in final edited form as: J Immunol. 2008 Aug 1;181(3):2124–2133. doi: 10.4049/jimmunol.181.3.2124

Table I. Summary of total CD8+IFNγ+ T cell response against 28 LCMV-specific epitopes in various systems analyzed.

Mouse H-2 Haplotype Immunogen Total Sum Response ± SDa
H-2b LCMV 35 ± 20 × 106
H-2b GPVNPV 22 ± 10 × 106
H-2Kb−/− LCMV 8.1 ± 6.3 × 106*
H-2Kb−/− GPVNPV 3.2 ± 2.4 × 106*
H-2bxa LCMV 10 ± 2.1 × 106*
H-2bxd LCMV 22 ± 11 × 106
H-2bxk LCMV 20 ± 12 × 106
H-2bxs LCMV 29 ± 19 × 106
H-2b rVACV-LCMV GPC/NP/L 1.7 ± 0.71 × 106*
H-2b Peptide pool 0.08 ± 0.05 × 106*
a

Cumulative CD8+IFNγ+ T cell responses to 28 LCMV-specific epitopes generated by individual peptide stimulation in IFN-γ ICCS assays. The total sum response represents an average value from individually analyzed mice (±SD) from at least two independent experiments. The statistical analysis compares values significantly different from those for the wild-type H-2b mice infected with LCMV.

*

p < 0.05 (Mann-Whitney t test).