Table 2.
Overall activity (ERSP), duration, and synchronization (ITC), and frequency of TMS-evoked EEG oscillations in schizophrenia and healthy comparison subjects.
| TMS-evoked EEG oscillation parameters | Healthy comparison subjects | Patients with Schizophrenia | Statistics (unpaired t-test) |
|---|---|---|---|
| Prefrontal Cortex (−15 55 35)* | (mean±SD) | (mean±SD) | |
| TMS-evoked oscillatory activity (ERSP, μV) | 107.5±8.8 | 91.8±4.2 | F=57.1 p=4.4*10−9 |
|
| |||
| TMS-evoked synchronization | 10.9±3.7 | 6.5±2.8 | F=9.5 p=3.7*10−3 |
|
| |||
| Natural Frequency (Hz) | 31.0±4.0 | 21.5±2.1 | F=108.9 p=1.0*10−12 |
|
| |||
|
Premotor Cortex (−25 −10 55)*
| |||
| TMS-evoked oscillatory activity (ERSP, μV) | 142.3±34.7 | 108.0±22.5 | F=16.4 p=2.3*10−4 |
|
| |||
| TMS-evoked synchronization (ITC) | 16.0±8.2 | 11.2±6.7 | F=5.9 p=0.02 |
|
| |||
| Natural Frequency (Hz) | 26.5±2.7 | 20.2±2.4 | F=49.1 p=2.4*10−8 |
|
| |||
|
Motor Cortex (−25 −25 55)*
| |||
| TMS-evoked oscillatory activity (ERSP, μV) | 149.1±34.4 | 125.5±26.0 | F=5.9 p=0.02 |
|
| |||
| TMS-evoked synchronization (ITC) | 19.3±8.5 | 16.0±6.0 | F=2.1 p=0.15 |
|
| |||
| Natural Frequency (Hz) | 21.8±2.9 | 19.2±2.5 | F=6.3 p=0.01 |
|
| |||
|
Parietal Cortex (−5 −45 50)*
| |||
| TMS-evoked oscillatory activity (ERSP, μV) | 108.8±15.9 | 100.7±20.6 | F=1.9 p=0.18 |
|
| |||
| TMS-evoked synchronization (ITC) | 24.1±9.3 | 23.9±10.1 | F=2.1 p=0.16 |
|
| |||
| Natural Frequency (Hz) | 19.9±1.9 | 18.7±2.5 | F=2.5 p=0.12 |
*
Talairach coordinates