Figure 5.
Methionine synthase activity in cortex of SJl/J and C57BL6/J mice with or without thimerosal treatment. Methionine synthase activity was measured in the presence of either methylcobalamin (MethylB12) or hydroxocobalamin (HydroxoB12). Activity was significantly lower in SJL/J autoimmune-prone mice compared to the C57BL6/J strain, irrespective of thimerosal treatment. Activity was higher in the presence of methylcobalamin. *P < 0.02 compared to C57BL6/J group, **P < 0.001 compared to C57BL6/J group.