Figure 5.
Comparison of brain vascular volume in wild-type (WT) and double knockout mice for astroglial Cx43 and Cx30 by in situ brain perfusion assays. [14C]sucrose distribution volume in the brain of WT and DKo mice were measured with albumin-free-bicarbonate buffer (open bars) and with albumin addition (40 g/L; filled bars) delivered by in situ brain perfusion at 2.5 mL/min for 120 seconds. Data are mean values±s.d. of five animals. *P<0.05 comparing WT and DKo mice; †P<0.05 comparing DKo with and without albumin perfusion fluid.