Table 1.
Regions in hiPSCs with Genomic Abnormalities
| Chromosome | Cell Line Identified | Region | Size | Z-Score | Mean (log2ratio) Fibroblast/ hiPSC |
No. of Genes | No. of miRNA |
|---|---|---|---|---|---|---|---|
| 7p11.2 | hiPSC2 | 56808738-62112547 | 5.3 Mb | 19.37 | 0.213 | 1 | 0 |
| 8q12.3 | hiPSC1 | 62203767-100955803 | 83.8 Mb | 45.26 | −0.185 | 148 | 3 |
| 9q34.3 | hiPSC2 | 137714842-139627239 | 1.9 Mb | 21.60 | 0.207 | 75 | 1 |
| hiPSC18 | 135323818-139634573 | 4.3 Mb | 21.38 | 0.138 | 102 | 1 | |
| 10q21.3 | hiPSC2 | 67642045-67930512 | 0.3 Mb | 19.24 | 0.473 | 1 | 0 |
| 11p11.12 | hiPSC2 | 48381190-55253892 | 6.9 Mb | 19.24 | 0.149 | 16 | 0 |
| 12p13.31 | hiPSC1 | 62119-11760562 | 11.7 Mb | 45.32 | −0.175 | 176 | 2 |
| 14q32.33 | hiPSC2 | 103616693-106182502 | 2.6 Mb | 19.71 | 0.163 | 27 | 1 |
| hiPSC18 | 103353890-106222351 | 2.9 Mb | 18.12 | 0.141 | 30 | 1 | |
| 16p13.3 | hiPSC2 | 7675-2208335 | 2.2 Mb | 19.30 | 0.172 | 104 | 2 |
| hiPSC18 | 53-2234072 | 2.2 Mb | 20.49 | 0.181 | 107 | 2 | |
| 19p13.3 | hiPSC2 | 208435-2449396 | 2.2 Mb | 24.08 | 0.213 | 86 | 2 |
| hiPSC18 | 40285-3774141 | 3.7 Mb | 24.35 | 0.170 | 121 | 2 | |
| 20q13.33 | hiPSC18 | 59860004-62429688 | 2.6 Mb | 18.50 | 0.154 | 81 | 7 |
| 21q22.3 | hiPSC1 | 38084180-46913738 | 8.8 Mb | 73.43 | 0.320 | 144 | 0 |
| 22q13.32 | hiPSC2 | 46997532-49534378 | 2.5 Mb | 21.66 | 0.177 | 37 | 0 |
| hiPSC18 | 40986242-49567312 | 8.6 Mb | 22.54 | 0.100 | 103 | 3 | |
| Xq21.1 | hiPSC1 | 77883731-90950867 | 13.1 Mb | 20.61 | 0.080 | 30 | 2 |
| hiPSC2 | 25192507-151731387 | 126.5 Mb | 31.42 | 0.122 | 714 | 69 | |
| Yp11.2-q11.21 | hiPSC2 | 2858143-20250487 | 17.4 Mb | 28.19 | 0.120 | 27 | 0 |