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. 2012 Oct 16;7(10):e47137. doi: 10.1371/journal.pone.0047137

Table 2. Somatic mutations that alter miRNA targeting in linkage disequilibrium blocks of association study markers.

Somatic mutation Cancer type Gene miRNA Germline mutation in target sitea Association study markera LD block boundaries Cancer type in association study P-Value
Chr4:g.96075969G>T Lung BMPR1B miR-125b rs1434536 (4) rs11097457 (844) 96061509–96091524 Breast Neoplasms [46] 1.97E-04
Chr19:g.51363764A>C Prostate KLK3 miR-138, miR-210, hsa-miR-675-5p rs1803136 (1) rs2735839 (859) 51361757–5134623 Prostatic Neoplasms [49] 2.00E-18
Chr5:g.141691500G>T Prostate SPRY4 miR-608 rs72117814 (1) rs4624820 (9712) 141664185–141693593 Testicular Neoplasms [53] 3.00E-13
a

: The number in parentheses below the name of the polymorphism is the distance, in bp, from the germline mutation to the somatic mutation.