Table 2.
Prediction performance of various baseline measurements and their combinations in terms of the AUC Score
| AUC score | |
|---|---|
| ADAS-cog total 11 |
0.7024 |
| ADAS-cog total 13 |
0.7248 |
| ADAS-cog subscore Q1 Word Recall |
0.6830 |
| ADAS-cog subscore Q2 Commands |
0.1581 |
| ADAS-cog subscore Q3 Construction |
0.4899 |
| ADAS-cog subscore Q4 Delayed Word |
0.6842 |
| ADAS-cog subscore Q5 Naming |
0.3202 |
| ADAS-cog subscore Q6 Ideational |
0.5142 |
| ADAS-cog subscore Q7 Orientation |
0.4836 |
| ADAS-cog subscore Q8 Word |
0.6062 |
| ADAS-cog subscore Q9 Recall |
0.2581 |
| ADAS-cog subscore Q10 Spoken |
0.3914 |
| ADAS-cog subscore Q11 Word Finding |
0.5436 |
| ADAS-cog subscore Q12 Comprehension |
0.2756 |
| ADAS-cog subscore Q14 Number Cancellation |
0.4451 |
| ADAS-cog subscore Q1-Q14 |
0.7598 |
| Age |
0.5123 |
| Years of Education |
0.5090 |
| MMSE Score |
0.5916 |
| CDR-SB |
0.6064 |
| ADAS total 13 + ADAS subscores |
0.7561 |
| ADAS total 13 + ADAS subscores + MMSE + CDR-SB |
0.7674 |
| FAQ |
0.6874 |
| LDEL: Logical Memory delayed |
0.6573 |
| LIMM: Logical Memory immediate |
0.6136 |
| MRI (237) |
0.7214 |
| Lab tests (18) |
0.5348 |
| APOE genotyping |
0.5473 |
| TRAA: Trail Making Test: Part A |
0.5944 |
| TRAA: Trail Making Test: Part B | 0.6187 |
The numbers in the second column are the leave-one-out AUC score which may be significantly lower than 0.5. The number in the parenthesis denotes the number of measurements involved.