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Summary of kinetics and binding data
| P1 | P1′ | P2′ | P3′ | P4′ | P5′ | P6′ | Vmax | Km | KD,apo | kcat | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| μmol/min/mg | μm | μm | s−1 | ||||||||
| Arg | Val | Tyr | Ile | His | Pro | Phe | AngIII | 29.8 ± 4.8 | 6.2 ± 2.0 | 5 ± 0.4 | 51 |
| Val | Val | Tyr | Ile | His | Pro | Phe | 9.4 ± 0.4 | 5.7 ± 1.9 | NDa | 17 | |
| Val | Tyr | Ile | His | Pro | Phe | AngIV | 9.7 ± 1.6 | 2.1 ± 0.3 | 15 ± 4.0 | 16 | |
| Arg | Tyr | Ile | His | Pro | Phe | 52.1 ± 4.1 | 2.5 ± 0.5 | ND | 89 |
a ND, not determined.
