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. 1980 Mar;77(3):1521–1525. doi: 10.1073/pnas.77.3.1521

Glyoxylate cycle in toad urinary bladder: possible stimulation by aldosterone.

D B Goodman, W L Davis, R G Jones
PMCID: PMC348527  PMID: 6929503

Abstract

A homogenate of the toad urinary bladder epithelial cell layer has the two enzymatic activities unique to the glyoxylate cycle--isocitrate lyase (threo-Ds-isocitrate glyoxylate-lyase, EC 4.1.3.1) and malate synthase [L-malate glyoxylate-lyase (CA-acetylating), EC 4.1.3.2]--as well as the capacity to carry out CN-insensitive palmitoyl-CoA oxidation. When tissue is incubated in the presence of a fatty acid substrate, tissue glycogen levels increase. Additionally, in the presence of aldosterone, glycogen levels are higher. These data demonstrate the presence of glyoxylate cycle enzymes in tissue of a higher animal and raise the possibility that such tissue can convert lipid to carbohydrate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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