Figure 8. Excitation of MCs by AON axons is manifested as accurately timed spikes in vivo.
(A-D) Data recorded from one cell. (A) A PSTH using time bins of 50 ms. (B) A PSTH of the same data as in A but with 1 ms time bins. The height of the bars indicates the percentage of trials in which firing occurred within the corresponding time bin. (C) The same PSTH as in B, shown in an enlarged scale. (D) PSTH as in C but for the optoelectric artifact that is produced by shining light on the metal electrode. Note the difference in latency between the biological action potentials and the artifact. (E-G) Population PSTHs from cells in which excitation was statistically identified. Mean is shown in black and standard error in red. Firing probabilities are normalized to the mean (E) Population PSTH obtained with 1 ms bins. Top PSTH is for 9 of 20 cells in which a statistical test identified excitation. Bottom PSTH is for all 20 cells. (F) The same PSTH as in E (top), shown in an enlarged scale. (G) A peri-response time histogram. The histogram is aligned to the response peak and not to the stimulus. Note the difference between F and G indicating that the breadth of the PSTH in F is mostly due to the latency differences between different experiments and not to the jitter of any one cell. (H) Population PSTH at 1 ms bin resolution for 11 cells from control animals.