Skip to main content
. Author manuscript; available in PMC: 2013 Mar 4.
Published in final edited form as: Mol Psychiatry. 2011 Nov 22;18(2):226–235. doi: 10.1038/mp.2011.155

Table 2.

Significantly associated blocks and haplotypes for genes in the NVC QTL

Gene
(study sample)		 Haplotype
block		 Block tagging
SNPs		 SNP base
pair position		 Associated
haplotypes		 Haplo
freq		 Haplo
P 		Block
P
KCND3 (AGP) 9th rs11102353a 112426542 TTb,c 0.20 0.008 0.02
rs1373291 112426874
KCND3 (AGRE) 15th rs1443928 112472773 CC 0.15 0.0001 0.0006
rs12025303 112474929
NGF (AGRE) 2nd rs2239622 115837709 TAA 0.27 0.003 0.001
rs2856813 115837919 CGC 0.52 0.009
rs2856811 115838282
NGF (AGRE) 3rd rs6686615 115845046 GT 0.41 0.0003 0.002
rs12058927 115846221 AT 0.42 0.03
NGF (AGRE) 4th rs10776797 115847295 TAGAG 0.59 0.0002 0.001
rs12760036 115848450 GAGGA 0.19 0.003
rs4626883 115849938
rs6537860 115856344
rs12145726 115857251
NGF (AGP) 5th rs10776798 115862254 CGCT 0.07 0.0005 0.02
rs4565713 115869499
rs17033692 115869850
rs10858074 115870310

Abbreviations: AGP, Autism Genome Project; AGRE, Autism Genetics Research Exchange; NGF, nerve growth factor; NVC, nonverbal communication; SNP, single-nucleotide polymorphism.

a

Human genome assembly HG19.

b

Allele codes are based on the + strand.

c

Haplotypes in bold italics are associated with higher NVC scores in the NVC trait distribution, reflecting a more severe deficit. Haplotypes not in bold are associated with lower NVC scores.