. 2011 Aug 8;8(5):388–403. doi: 10.1038/cmi.2011.26

Table 2. Changes in cytokine expression reported in in vivo endotoxin tolerance conditions. Adopted and modified from reviews^{19, 200}.

Cytokine	Change in expression	In vivo studies of endotoxin tolerance
TNF-α	↓	Human,^{46, 201, 202, 203} pig,²⁰⁴ rabbit,²⁰⁵ guinea pig,²⁰⁶ rat,²⁰⁷ mouse^{200, 208}
IL-1β	↓	Human,²⁰² rabbit,²⁰⁵ mouse²⁰⁸
	↑	Mouse³⁰
IL-6	↓	Human,^{201, 202} guinea pig,²⁰⁶ mouse^{208, 209}
	↑	Human²⁰³
IL-8	↓	Human^{201, 202, 203}
IL-10	↓	Rat,²¹⁰ mouse²¹¹
IL-12	↓	Mouse⁵¹
G-CSF	↓	Human,^{202, 203} mouse^{208, 212}
IFN-γ	↓	Mouse^{51, 213}
TGF-β	↑	Mouse⁴⁶

Abbreviations: G-CSF, granulocyte-colony stimulating factor; IFN, interferon; TGF, transforming growth factor; TNF, tumor-necrosis factor; ↑, increased expression; ↓, decreased expression.

Table 2. Changes in cytokine expression reported in in vivo endotoxin tolerance conditions. Adopted and modified from reviews19, 200.

Table 2. Changes in cytokine expression reported in in vivo endotoxin tolerance conditions. Adopted and modified from reviews^{19, 200}.