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. Author manuscript; available in PMC: 2014 Apr 24.
Published in final edited form as: Neuron. 2013 Apr 4;78(2):256–268. doi: 10.1016/j.neuron.2013.02.026

Figure 1. Genome-wide signal intensity (Manhattan) plots showing the individual P values (based on fixed-effects meta-analysis) against genomic position.

Figure 1

The results for the association of CSF tau (a), and ptau (b) levels with 5,815,690 SNPs are shown. Within each chromosome, shown on the x axis, the results are plotted left to right from the p-terminal end. Horizontal dashed lines indicate P value thresholds of 1 × 10−5 and 5 × 10−8 (genome-wide significance).