. 2013 Feb 15;8(3):317–332. doi: 10.4161/epi.23989

Table 1. Most of the myogenesis-associated differential methylation does not display a simple correlation with expression levels of the closest gene^a.

	Number of genes with significant expression differences in Mb or Mt vs. non-myogenic cell cultures
Gene sets	Upreg > 2x	Dnreg > 2x	No change in expression in myogenic cells
Genes with > 1 hypermeth site	84	64	128
Genes with > 1 hypometh site	174	106	307
All genes	2076	1473	5265
Ratio of hyper to hypo-meth genes	0.48	0.60	0.42

^a Hyper- or hypo-methylated sites in myogenic progenitor cells were mapped to genes by closestBed analysis. The number of genes with more than a 2-fold change in expression refers to genes with significant (adjusted p < 0.01) up- or down-regulation of either Mb or Mt vs. 19 non-muscle cultures as determined with an exon expression microarray.

Table 1. Most of the myogenesis-associated differential methylation does not display a simple correlation with expression levels of the closest genea.

Table 1. Most of the myogenesis-associated differential methylation does not display a simple correlation with expression levels of the closest gene^a.