Fig. 4.
Treatment with CD49d decreased CNS dissemination of RSV. BALB/c mice were infected intranasally with RSV and received a single dose of 70 µg anti-CD49d blocking antibody intravenously. Three days postinfection, mice were killed and the tissues prepared for RNA extraction. Data in the graph show the number of copies of RSV nucleoprotein transcripts in the brains of controls animals and animals treated with anti-CD49d antibody. Statistical analysis, one-way ANOVA; **P < 0.05, n = 5 per treatment.