Table 2.
Immunogenicity of sciIV in ferrets
| Treatment | Collection timea | Sera GMTb |
|
|---|---|---|---|
| HAI | VNA | ||
| PBS | Prebleed | <10 | <10 |
| Prime only | <10 | <10 | |
| Prime + boost | <10 | <10 | |
| pH1N1/E3-sciIV | Prebleed | <10 | <10 |
| Prime only | 40 | 64 | |
| Prime + boost | 64 | 160 | |
| Convalescent-phase serac | 1,800 | 3,600 | |
a
Vaccinations were administered at 4 week intervals; samples were collected 4 weeks after the indicated dose.
b
Data were calculated from 3 immunized or 2 convalescent individual animals. VNA, virus neutralization assay.
c
Ferrets were inoculated with a nonlethal dose of A/California/07/2009; sera were collected 4 weeks later.