Figure 3. CXCL5 inhibits chemokine scavenging in whole blood in vitro and in vivo.
The plasma concentrations of CXCL1 (A), CXCL2 (B) and CXCL5 (C) were measured by ELISA after incubation of the citrated blood from WT and Cxcl5−/− mice (n=3 mice/group) with recombinant CXCL1, CXCL2 and CXCL5 respectively for 15 minutes. The plasma concentrations of CXCL1 (D), CXCL2 (E) and CXCL5 (F) in the plasma of WT and Cxcl5−/− mice were measured at different time points after intravenous injection of recombinant CXCL1, CXCL2 and CXCL5 respectively. Data are representative of two independent experiments. N.D: not detected. *P<0.05; ***P<0.001.