Table 2.
Striatal plaque scores compared to average cortical measures of Alzheimer’s disease-associated histopathology. All values are the median followed by mean and standard deviation. The AD group had significantly higher total striatal plaque score, striatal cored/neuritic plaque score, total cortical plaque score, total cortical tangle score, CERAD neuritic plaque density and Braak stage than the normal elderly control group.
| Diagnosis (N) | Striatal Total Plaque Score | Striatal Neuritic & Cored Plaque Score | Cortical Total Plaque Score | Cortical CERAD Neuritic Plaque Density | Cortical Total Tangle Score | Braak NFT Stage |
|---|---|---|---|---|---|---|
| Control (87) | 0 | 0 | 5 | 1 | 4.2 | 3 |
| 0.5 (0.8) | 0.1 (0.3) | 5.7 (5.3) | 1.3 (1.1) | 4.5 (2.5) | 3.0 (0.9) | |
| AD (124) | 3 | 0.5 | 14.5 | 3 | 14.5 | 5 |
| 2.4 (0.9) | 0.75 (0.6) | 13.7 (2.0) | 2.9 (0.3) | 12.0 (3.8) | 5.0 (0.9) |