Table 3.
Distribution of functional mutation carriers within the population distribution for longitudinal SBP.
| Bottom 10% | Top 10% | Bottom 20% | Top 20% | Bottom 30% | Top 30% | Bottom 40% | Top 40% | *Bottom 50% | Top 50% | |
|---|---|---|---|---|---|---|---|---|---|---|
| NCCT Carriers (%) | 3 (11.1) | 1 (3.7) | 6 (22.2) | 3 (11.1) | 10 (37.0) | 3 (11.1) | 13 (48.2) | 5 (18.5) | 20 (74.1) | 7 (25.9) |
| NKCC2 Carriers (%) | 2 (18.2) | 0 (0) | 2 (18.2) | 1 (9.1) | 3 (27.3) | 1 (9.1) | 5 (45.4) | 1 (9.1) | 9 (81.8) | 2 (18.3) |
| ROMK Carriers (%) | 4 (33.3) | 0 (0) | 5 (41.7) | 1 (8.3) | 6 (50.0) | 1 (8.3) | 9 (75.0) | 1 (8.3) | 11 (91.7) | 1 (8.3) |
| All Carriers (%) | 9 (18.4) | 1 (2.0) | 13 (26.5) | 5 (10.2) | 19 (38.8) | 5 (10.2) | 27 (55.1) | 7 (10.2) | 39 (79.6) | 10 (20.4) |
| Non-Carriers | 304 | 312 | 613 | 621 | 920 | 934 | 1225 | 1245 | 1633 | 1443 |
| Fisher's exact/Chi square | P = 0.02 | P = 0.09 | P = 0.006 | P = 0.0008 | P = 0.0002 | |||||
*
Based on numbers of carriers and non-carriers above and below the population mean of 0.