Table 1. VOCs detected in lung diseases.
| Author | Disease | Significant VOCs identified |
|---|---|---|
| Phillips 2003 (13) | Lung Cancer | butane; 3-methyl tridecane; 7-methyl tridecane; 4-methyl octane; 3-methyl hexane; heptane; 2-methyl hexane, pentane; 5-methyl decane |
| Machado 2005 (14) | Lung Cancer | isobutane; methanol; ethanol; acetone; pentane; isoprene; isopropanol; dimethylsulfide; carbon disulfide; benzene; toluene |
| Poli 2005 (15) | Lung Cancer (NSCLC) | 2-methyl pentane; pentane; ethyl benzene; xylenes (total); trimethyl benzene; toluene; benzene; decane; octane; penta methyl heptane |
| Barker 2006 (16) | Cystic Fibrosis | ethane; propane; pentane*#; methanolθ; ethanol; 2-propanol#; acetone; isopreneθ; benzene; toluene; dimethyl sulfide#θ; limonene |
| Dragonieri 2007 (17) | Asthma | 4 methyl octane; 2,4-dimethyl heptane; isopropanol; toluene; isoprene; alkane; acetic acid; acetone; 2,6,11-trimethyl dodecane; 3,7-dimethyl undecane; 2,3-dimethyl heptane |
| Chen 2007 (18) | Lung cancer | styrene; decane; isoprene; benzene; undecane; 1-hexene; hexanol; propyl benzene; 1,2,4-trimethyl benzene; heptanal; methyl cyclopentane |
| Peng 2010 (19) | Lung, breast, colon, prostate cancer | 16 compounds identified that varied in abundance between healthy groups and cancer groups-1-methyl-4-(1-methyl)benzene; toluene; dodecane; 3,3-dimethyl pentane; 2,3,4-trimethyl hexane; 1,1'-(1-butenylidene) bis benzene; 1,3-dimethyl benzene;1-iodo nonane; (1,1-dimethylethyl thio) acetic acid; 4-(4-propylcyclohexyl)-4'-cyano[1,1'-biphenyl]4-yl ester benzoic acid; 2 amino-5-isopropyl-8-methyl-1-azulenecarbonitrile; 5-(2-methylpropyl) nonane; 2,3,4-trimethyl decane; 6-ethyl-3-octyl ester 2 trifluromethyl benzoic acid; p-xylene; and 2,2-dimethyldecane |
| Fuchs 2010 (20) | Lung cancer | Aldehydes-butanal; formaldehyde; acetaldehyde; pentanal; hexanal; octanal; nonanal |
| Wang 2012 (21) | Lung cancer | Adenocarcinoma-2,4,6-trimethyloctane; 2-methyldodecane; 2-tridecanone; 2-pentadecanone; 8-methy lheptadecane; 2-heptadecanone; nonadecane; eicosane; squamous-methanoic acid; 2-nonanone; 2-pentadecanone; nonadecane; eicosane; SCC-2-decanone; 2-hendecanone; 2-methylnaphthaline; 2-tridecanone; 2-pentadecanone; 2,6-dimethylnaphthaline; 1- heptadecanol; 2-heptadecanone; nonadecane; eicosane |
VOCs, volatile organic compounds. #sig diff from control group; *difference with antibiotics, body mass, Pseudomonas infection; θdifference with diabetics.