Figure 2.
A schematic illustration of glutamate transporter distributions around parallel fiber synapses on Purkinje cell spines in the molecular layer of the cerebellum. EAAT1 is expressed in the astrocytes (Bergmann glial cells) at very high levels, and about six times higher than EAAT2 (162, 184). Most of the EAAT4 protein is found in cerebellar Purkinje cells (the glia-covered parts of the membranes of Purkinje cell dendrites), but low levels are also found in scattered neurons in the neocortex (123). EAAT3 is also found in the Purkinje cell dendrites, as well as in the other neuron types present, but at low levels (193) (Copyright: Neurotransporter.org; Reproduced with permission).