Table 1.
Overview of the nomenclature of plasma membrane GABA transporters.
| Name adopted by HUGO (www.genenames.org) | Other names |
|---|---|
| GABA transporter 1 (GAT1; slc6a1) | Rat GAT1, human GAT1, mouse GAT1 (51, 52) |
| GABA transporter 2 (GAT2; slc6a13) | Rat GAT2, human GAT2, mouse GAT3 (52, 277) |
| GABA transporter 3 (GAT3; slc6a11) | Rat GAT3, hGAT-3, mGAT4, GAT-B (52, 277, 278) |
| Betaine-GABA transporter (BGT1; slc6a12) | Rat BGT1, rat GAT-4, rat NTBE, human GAT-4, mouse GAT2 (52–56, 180) |
| Taurine transporter (TAUT; slc6a6) | (279), (280) |
| Proton-coupled amino acid transporter 1 (PAT1; slc36a1) | Imino acid carrier, LYAAT-1, tramdorin 3 (281) |
The neurotransmitter transporter family (SLC6) comprises four GABA transporters as well as the taurine transporter (280). Both the taurine transporter and the proton-coupled amino acid transporter 1 (282) are able to transport GABA, but with low affinity (Km > 1 mM) and are therefore usually not classified as “GABA transporters.” The nomenclature used here is the one adopted by the HUGO Gene Nomenclature Committee (283).